ALPS Study Concludes: No Overall Survival Increase From Amiodarone, Lidocaine After Out-of-Hospital Arrest

“Anti arrhythmic drugs are used commonly in out-of-hospital cardiac arrest for shock-refractory ventricular fibrillation or pulseless ventricular tachycardia, but without proven survival benefit.  In this randomized, double-blind trial, researchers compared parenteral amiodarone, lidocaine, and saline placebo, along with standard care, in adults who had non-traumatic out-of-hospital cardiac arrest, shock-refractory ventricular fibrillation or pulseless ventricular tachycardia … Read more